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Use the DNA template strand below to synthesize a polypeptide. Write your answer in the box below. Use the one-letter amino acid abbreviations in your answer (see figure 7.7). For example, if you determine the amino acid sequence is serine-proline-lysine, type SPK as your answer.Template strand: AATACGGCC

Question

Use the DNA template strand below to synthesize a polypeptide. Write your answer in the box below. Use the one-letter amino acid abbreviations in your answer (see figure 7.7). For example, if you determine the amino acid sequence is serine-proline-lysine, type SPK as your answer.Template strand: AATACGGCC

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Solution

To synthesize a polypeptide from the given DNA template strand, we first need to transcribe the DNA into mRNA, and then translate the mRNA into a polypeptide.

  1. Transcription: The DNA template strand is transcribed into mRNA. In this process, adenine (A) pairs with uracil (U), thymine (T) pairs with adenine (A), cytosine (C) pairs with guanine (G), and guanine (G) pairs with cytosine (C). So, the DNA template strand AATACGGCC will be transcribed into mRNA as UUAUGCCGG.

  2. Translation: The mRNA is then translated into a polypeptide. This is done by reading the mRNA sequence in groups of three nucleotides, known as codons. Each codon codes for a specific amino acid.

    The mRNA sequence UUAUGCCGG translates into the following codons: UUA, UGC, CGG.

    Using the standard genetic code, these codons correspond to the following amino acids:

    UUA - Leucine (L) UGC - Cysteine (C) CGG - Arginine (R)

So, the polypeptide synthesized from the DNA template strand AATACGGCC is LCR.

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