Which of the following best defines a compound that binds non-covalently to the active site of an enzyme to block its activity? A product An irreversible inhibitor An affinity label A substrate A competitive inhibitor
Question
Which of the following best defines a compound that binds non-covalently to the active site of an enzyme to block its activity? A product An irreversible inhibitor An affinity label A substrate A competitive inhibitor
Solution
A compound that binds non-covalently to the active site of an enzyme to block its activity is best defined as a competitive inhibitor.
Here's why:
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A product is what is formed after the enzyme has catalyzed a reaction, so it doesn't block the enzyme's activity.
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An irreversible inhibitor binds to the enzyme and permanently deactivates it, usually through a covalent bond, not a non-covalent one.
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An affinity label is a molecule that binds to an enzyme and then covalently modifies it, which is not the case here.
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A substrate is a molecule upon which an enzyme acts to carry out a chemical reaction, not to block its activity.
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A competitive inhibitor competes with the substrate for the
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