n staphylococcal skin infection there is neutrophilic infiltrate causing tissue damage. Thetissue damage is most likely caused due to:Select one:a. Activation of caspasesb. Generation of superoxidec. Release of cytochrome cd. Release of cytosolic calcium
Question
n staphylococcal skin infection there is neutrophilic infiltrate causing tissue damage. Thetissue damage is most likely caused due to:Select one:a. Activation of caspasesb. Generation of superoxidec. Release of cytochrome cd. Release of cytosolic calcium
Solution
The tissue damage in staphylococcal skin infection is most likely caused by:
b. Generation of superoxide
Here's why:
Staphylococcus bacteria, like Staphylococcus aureus, can cause skin infections. These bacteria are capable of producing a variety of toxins that can cause tissue damage. One of the ways they do this is by generating reactive oxygen species (ROS), such as superoxide.
Neutrophils, a type of white blood cell, are part of the body's immune response to such infections. They attempt to kill the bacteria by engulfing them in a process called phagocytosis. During this process, the neutrophils generate superoxide, a type of ROS, to kill the bacteria. However, this can also cause collateral damage to the surrounding tissues, leading to inflammation and tissue damage.
The other options listed - activation of caspases, release of cytochrome c, and release of cytosolic calcium - are more related to processes of programmed cell death (apoptosis) rather than the inflammatory response to bacterial infection.
Similar Questions
Redness and swelling in an infected area is due to:A large number of disease-causing microbes.Heat produced by the invading microbes.More rapid blood flow to the area.The skin producing defence cells.
Why are there lots of neutrophil "bodies" collected around the site of an injury (pus)?
X-linked agammaglobulinemia:The case:Alvin was well during the first 10 months, but then presented with several bouts of otitis media and asevere case of streptococcal infection of skin. During the next two years, Alvin continued to have ahistory of repeated infection of sinuses and ears and had 2 episodes of pneumonia. Tested with verylow IgG, no detectable IgM or IgA. Flow cytometry revealed circulating lymphocytes positive forCD3, CD4, and CD8 but did not detect lymphocytes with CD19. Mitogenic responses to PHA, conca-navalin A, tetanus toxoid, and diphtheria toxoid were normal. No response to anti-IgM(H+L) in pres-ence of IL-4. Also, the boy had no discernible tonsils (remember, tonsils are 80-90% B cells). Alvinwas treated successfully with intravenous gamma globulin (IVIG). The mother had two brothers whodied during infancy from pneumonia at a time before use of antibiotics. The mother has two sisterswho are well.
The damage to cells and tissues that leads to disease1 pointIs always directly due to replication of a pathogenCan never occur without infectionCan be due to excessive inflammationIs always a result of toxic by-products of pathogens
Inflammation may result in the formation of an abscess, a painful collection of pus which is formed by _______________________.antibody-antigen complexes, lymphocytes and cell debris.platelets, plasma and bacteria.dead and dying phagocytes, bacteria, plasma and cell debris.mainly dead and dying lymphocytes and bacteria.
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.