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How is translation initiated?Two ribosomal subunits bind to the DNA sequence.DNA helicase binds to the origins of replication.RNA polymerase binds to the promoter sequence.Two ribosomal subunits bind to the mRNA transcript.

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How is translation initiated?Two ribosomal subunits bind to the DNA sequence.DNA helicase binds to the origins of replication.RNA polymerase binds to the promoter sequence.Two ribosomal subunits bind to the mRNA transcript.

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Solution 1

Translation is initiated in the following steps:

  1. The first step in translation is the binding of the smaller ribosomal subunit to the mRNA transcript. This is guided by the ribosome recognizing and binding to a specific sequence on the mRNA called the ribosome binding site or the Shine-Dalgarno sequence in prokaryotes.

  2. The initiator tRNA molecule, carrying the amino acid methionine, binds to the start codon (AUG) on the mRNA transcript. This is facilitated by several initiation factors.

  3. The larger ribosomal subunit then binds to the smaller one to form the complete initiation complex, ready for the elongation phase of protein synthesis.

Note: Translation occurs on mRNA, not DNA. The steps you mentioned about DNA helicase and RNA polymerase are part of DNA replication and transcription respectively, not translation.

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Solution 2

Translation is initiated in the following steps:

  1. The first step in translation is the binding of a small ribosomal subunit to the mRNA. This is facilitated by initiation factors that help in the recruitment of the small ribosomal subunit to the mRNA.

  2. The small ribosomal subunit then scans the mRNA for the start codon (AUG). The start codon is recognized by the anticodon of the initiator tRNA molecule.

  3. Once the start codon is recognized, the large ribosomal subunit associates with the small subunit to form the complete initiation complex. This is again facilitated by initiation factors.

  4. The ribosome then begins to move along the mRNA, decoding its genetic information and synthesizing the corresponding polypeptide chain. This process is known as elongation.

  5. The process of translation is terminated when a stop codon is encountered. The newly synthesized polypeptide is then released from the ribosome, and the ribosome dissociates into its large and small subunits.

Note: The process of translation is not initiated by the binding of ribosomal subunits to the DNA sequence or by the binding of DNA helicase to the origins of replication. These are steps in the process of DNA replication, not translation. Similarly, the binding of RNA polymerase to the promoter sequence is a step in transcription, not translation.

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Similar Questions

During the process of translation:Select one:a. The incoming tRNA must first bind to the E siteb. Initiation begins with the binding of the ribosomal larger subunit to the polyA tail of the mRNAc. The peptide is passed from tRNA in the P site to the tRNA at the A sited. The mRNA is translated by one ribosome at a time

Translation of mRNA in bacterial cells begins when A. An amino acid is added to the C-terminus of a polypeptide chain B. The initiator fMet-tRNA binds to a free 30S ribosomal subunit C. Peptidyl transferase catalyzes transpeptidation between adjacent amino acids D. The ribosome disengages from mRNA

Which of the following statements about translation are true.0 / 1 pointPost-translational modifications is the binding of repressor proteins to a sequence found on an mRNA molecule.A ribosome has two subunits. The large subunit finds the mRNA to begin translation, while the small subunit has two sites for amino acids to bind.Translation is performed by ribosomes in both prokaryotes and eukaryotes.Transfer RNA (tRNA) are used to bring the next amino acid to add to the polypeptide chain by matching to the next codon in the mRNA being translated. After the amino acid is added, the tRNA can then be repurposed for a different amino acid and codon pairing.IncorrectThis is incorrect. The small subunit finds the mRNA to begin translation, while the large subunit has two sites for amino acids to bind. The A site accepts transfer RNA (tRNA) bearing an amino acid, while the P site binds the tRNA to the growing chain.

During the process of translation, the growing polypeptide chain is released from the ribosome when:Select one:a. The 7-methylguanosine cap is reachedb. A chain terminating tRNA binds to the ribosomec. The poly A tail is reachedd. A chain terminating codon is reached

Transcription occurs in the ________.  Translation occurs in the _________.

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