Explain how a pathogen causes a fever.2. Explain why pyrexia, but not hyperthermia, is considered the second line of defence.3. What is a febrile seizure?4. Explain how the interferons and complement proteins participate in the destruction of pathogens and fight infection.
Question
Explain how a pathogen causes a fever.2. Explain why pyrexia, but not hyperthermia, is considered the second line of defence.3. What is a febrile seizure?4. Explain how the interferons and complement proteins participate in the destruction of pathogens and fight infection.
Solution
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A pathogen causes a fever by triggering an immune response in the body. When a pathogen enters the body, it is recognized by immune cells which release chemicals called pyrogens. These pyrogens travel to the hypothalamus in the brain, which controls body temperature. The pyrogens cause the hypothalamus to raise the body's temperature, resulting in a fever.
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Pyrexia, or fever, is considered the second line of defense because it is a response to an infection or illness. It is the body's way of trying to kill off the pathogens by creating an environment that is too hot for them to survive. Hyperthermia, on the other hand, is an abnormally high body temperature that is not caused by a response to infection or illness. It can be caused by external factors such as heat stroke or certain medications. Therefore, it is not considered a defense mechanism.
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A febrile seizure is a convulsion in a child that is caused by a spike in body temperature, often from an infection. These seizures occur in infants and small children between the ages of 6 months and 5 years. While they can be frightening to watch, they are usually harmless and typically don't indicate a serious health problem.
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Interferons and complement proteins are part of the immune system's response to infection. Interferons are proteins that are produced by cells in response to viral infection. They interfere with the ability of viruses to replicate within infected cells and also stimulate other immune cells to attack the infection. Complement proteins, on the other hand, are part of the immune system's innate response. They help or 'complement' the ability of antibodies and phagocytic cells to clear pathogens from an organism. They do this by opsonizing, or coating, pathogens which enhances their recognition by immune cells, leading to their destruction.
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