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Which of the statements below relating to how a white blood cell travels to the site of infection are TRUE?i. Movement of the white blood cell in the extracellular matrix is facilitated by hyaluronidase.ii. Erythrocytes are flexible and can readily squeeze between endothelial cells.iii. The white blood cell responds to molecular signals from nearby cells.iv. The white blood cell squeezes between the simple squamous cells lining the blood vessel.

Question

Which of the statements below relating to how a white blood cell travels to the site of infection are TRUE?i. Movement of the white blood cell in the extracellular matrix is facilitated by hyaluronidase.ii. Erythrocytes are flexible and can readily squeeze between endothelial cells.iii. The white blood cell responds to molecular signals from nearby cells.iv. The white blood cell squeezes between the simple squamous cells lining the blood vessel.

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Solution

i. TRUE - Hyaluronidase is an enzyme that helps white blood cells move through the extracellular matrix by breaking down hyaluronic acid, a major component of the matrix.

ii. FALSE - Erythrocytes, or red blood cells, are indeed flexible, but they do not typically squeeze between endothelial cells. This process, known as diapedesis, is characteristic of white blood cells, not red blood cells.

iii. TRUE - White blood cells respond to molecular signals, such as chemokines and cytokines, from nearby cells. This process, known as chemotaxis, guides them to the site of infection or inflammation.

iv. TRUE - The process of a white blood cell squeezing between the simple squamous cells lining the blood vessel is known as diapedesis. This is a key step in the migration of white blood cells to the site of infection.

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