You wish to clone a laboratory rat, for that you have taken the female rat egg, de-nucleated and now going to put a Donor nucleus into it. Why type of cell would be best (as a donor) to take the nucleus from and why? [Note: You will not be using any specialized transcriptional factors from outside in this experiment] Adult somatic cells because they are not fully differentiated Early embryonic stem cells because they can achieve the totipotency easily Somatic cells from newborn rat because they are rapidly growing Epithelial cells because of their scutoid shape
Question
You wish to clone a laboratory rat, for that you have taken the female rat egg, de-nucleated and now going to put a Donor nucleus into it. Why type of cell would be best (as a donor) to take the nucleus from and why? [Note: You will not be using any specialized transcriptional factors from outside in this experiment] Adult somatic cells because they are not fully differentiated Early embryonic stem cells because they can achieve the totipotency easily Somatic cells from newborn rat because they are rapidly growing Epithelial cells because of their scutoid shape
Solution
The best type of cell to take the nucleus from would be early embryonic stem cells because they can achieve totipotency easily. Totipotency refers to the ability of a single cell to divide and produce all the differentiated cells in an organism, including extraembryonic tissues. Early embryonic stem cells are in a state of pluripotency, meaning they can become any type of cell in the body. This makes them ideal for cloning purposes as they can easily be reprogrammed to become any type of cell needed. Adult somatic cells, on the other hand, are already differentiated and would require additional steps to reprogram them to a pluripotent state. Similarly, somatic cells from a newborn rat, while rapidly growing, are also already on their way to differentiation. Epithelial cells, despite their unique scutoid shape, are also differentiated cells and would not be ideal for this purpose.
Similar Questions
The diagram below shows how a new cell that is genetically identical to to the patient is created for therapeutic cloning.The newly created cell is stimulated to divide and a blastocyst will form.Stem cells can be taken from the blastocyst and triggered to differentiate into any cells that are needed.Match the statements below to show whether they are a benefit or a problem with therapeutic cloning.ProblemBenefitPossible AnswersTransplanted tissues are likely to be rejected by the patient.Growing organs from stem cells of an embryonic clone of the patient would reduce the waiting time for organ transplants.It is a much easier process than bone marrow donation.Therapeutic cloning requires the creation and then destruction of an embryo that could develop into a human if allowed.I DON'T KNOWRESETSUBMIT ANSWER
why shouldn´t we clone human cells
The diagram below shows how a new cell that is genetically identical to the patient is created for therapeutic cloning. An ovum is another term for an egg cell.The newly created cell is stimulated to divide and the blastocyst will form.Stem cells can be taken from the blastocyst and triggered to differentiate into any cells that are needed.Which of the following is a benefit of therapeutic cloning?Stem cells from an embryo can differentiate into many different types of cell.The drugs taken before egg donation can have serious side effects.Therapeutic cloning requires the creation and then the destruction of an embryo that could develop into a human if allowed.Any produced tissues or organs are very unlikely to be rejected by the patient.
Which of the following is a benefit of therapeutic cloning?Stem cells from an embryo can differentiate into many different types of cell.The drugs taken before egg donation can have serious side effects.Therapeutic cloning requires the creation and then the destruction of an embryo that could develop into a human if allowed.Any produced tissues or organs are very unlikely to be rejected by the patient.
Which of the following is an advantage of embryonic stem cells compared with adult stem cells?There are potential ethical issuesThey are totipotentThey are multipotentThey could be rejected when transplanted into an adult
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