Le diabète de type 2 estADu à une destruction auto-immune des cellules b des ilots de langerhansBLié à des anomales de l'insulino-sécrétion et l'insulino-sensibilitéCAssocie fréquemment aux deux haplotypes hla dr3 et dr4DCaractérisé par une insulite constante au début de la maladieECaractérisé par la présence d'anticorps anti-gad au début de la maladie2021

Which of the following best describes the pathogenesis of Type 2 DiabetesMellitus?a. It is related to HLA-linked diabetogenic genesb. It is the result of insulin resistance coupled with β cell dysfunctionc. It is caused by immune-related progressive decline in β cell massd. It is the result of AGE-RAGE interactionse. It is the effect of activation of protein Kinase C

Type I diabetes is characterised by a total lack of insulin caused by:Question 1Answera.A reduced inflammatory responseb.Less than 50% beta cell destructionc.Acute autoimmune attack on beta cellsd.Helper T cells inhibiting macrophage function within the pancrease.T lymphocytes reacting against beta cells antigens

Discuss risk factors, pathogenesis, diagnosis and complications of type -1 & type-2diabetes mellitus

Which of these statements is correct in relation to Type 2 Diabetes?Question 37Answera.Type 2 diabetes is characterised by T-cell and macrophage-mediated destruction of β-cells (insulin-producing cells) in the pancreasb.Type 2 diabetes is an autoimmune condition associated with individuals possessing certain MHC proteins on their cells.c.Type 2 diabetes can typically be well managed with insulin injections.d.Type 2 diabetes is the more common form of diabetes (particularly in Western societies).e.Type 2 diabetes has no association at all with genetic predisposition

Individuals with type 2 diabetes Group of answer choices have pancreases that produce and secrete very little insulin. have an absolute requirement for insulin injections. may often control their disease by diet and exercise. have normal concentrations of glucose in their blood.