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Which of the following is not a modification to the mRNA before leaving the nucleus?Exon splicingEnd cappingPromoter bindingIntron removal

Question

Which of the following is not a modification to the mRNA before leaving the nucleus?Exon splicingEnd cappingPromoter bindingIntron removal

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Solution

The modification that does not occur to the mRNA before it leaves the nucleus is Promoter binding.

Here's why:

  1. Exon Splicing: This is a process where the non-coding regions (introns) are removed from the pre-mRNA and the coding regions (exons) are joined together.

  2. End Capping: This is the addition of a 5' cap to the pre-mRNA. This cap is a modified guanine nucleotide and it helps to protect the mRNA from degradation and assists in the export of the mRNA from the nucleus.

  3. Promoter Binding: This is not a modification of mRNA. Instead, it is a part of the process of transcription initiation. The promoter is a DNA sequence that the transcription machinery, including RNA polymerase and a number of other proteins, binds to.

  4. Intron Removal: This is similar to exon splicing. The introns, or non-coding regions, are removed from the pre-mRNA to produce the final mRNA molecule.

So, the correct answer is Promoter binding.

This problem has been solved

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