The lagging strand of DNA is replicated in a discontinuous manner. In this process, Okasaki fragments:
Question
The lagging strand of DNA is replicated in a discontinuous manner. In this process, Okasaki fragments:
Solution
The lagging strand of DNA is replicated discontinuously, in the opposite direction to the unwinding DNA. This process involves the creation of Okazaki fragments. Here are the steps:
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The replication fork moves along the DNA strand, unwinding it and separating the two strands.
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On the leading strand, DNA polymerase synthesizes a new strand of DNA continuously, in the same direction as the unwinding DNA.
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On the lagging strand, DNA polymerase synthesizes new DNA in the opposite direction to the unwinding DNA. Because of this, it cannot work continuously as it does on the leading strand.
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Instead, an enzyme called primase synthesizes a short RNA primer on the lagging strand. This primer acts as a starting point for DNA polymerase.
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DNA polymerase then adds nucleotides to the RNA primer, creating a short segment of DNA. This segment is an Okazaki fragment.
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When DNA polymerase reaches the RNA primer of the previous Okazaki fragment, it detaches.
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The RNA primer is then removed and replaced with DNA by another enzyme. This leaves a gap in the sugar-phosphate backbone of the DNA.
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The enzyme DNA ligase then seals this gap, joining the Okazaki fragments together into a continuous strand.
This process repeats along the length of the lagging strand, creating a series of Okazaki fragments that are eventually joined together to form a complete DNA strand.
Similar Questions
The lagging strand of DNA is replicated in a discontinuous manner. In this process, Okasaki fragments:Group of answer choicesare synthesized in the 5'→3' direction, and each one has its own RNA primer.are synthesized in the 3'→5' direction, and each one has its own RNA primer.are synthesized in the 5'→3' direction, and each one has its own DNA primer.are synthesized in the 3'→5' direction, and each one has its own DNA primer.
Why is the lagging strand synthesised in Okazaki fragments? Group of answer choicesBecause it is synthesised towards the replication forkBecause DNA polymerase III can only synthesise short fragmentsBecause it is synthesised by DNA polymerase I, which can only do short regions Because it is synthesised away from the replication fork
Okazaki fragments are the result of DNA polymerisation ofGroup of answer choicesthe lagging strand towards the replication fork the lagging strand away from the replication fork the leading strand towards the replication fork the leading strand away from the replication fork
The strand that produces Okazaki fragments.Group of answer choiceslagging strandleading strandboth leading and lagging strandNext
In DNA replication, continuously synthesis occurs on the leading strandMultiple choice question.without RNA primers.toward the origin of replication.in the 5' to 3' direction.and creates Okazaki fragments.
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