Which of the following statements is correct about poliovirus replication. Group of answer choicesThe virus must integrate its genome into the host DNA before replication.After assembly has taken place the viruses can be released without host cell lysis.Not all proteins encoded by the polivirus genome form part of the capsid.The polyprotein is cleaved once into a structural and a non-structural protein.
Question
Which of the following statements is correct about poliovirus replication. Group of answer choicesThe virus must integrate its genome into the host DNA before replication.After assembly has taken place the viruses can be released without host cell lysis.Not all proteins encoded by the polivirus genome form part of the capsid.The polyprotein is cleaved once into a structural and a non-structural protein.
Solution
The correct statement about poliovirus replication is: "Not all proteins encoded by the poliovirus genome form part of the capsid."
Here's why:
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Poliovirus is an RNA virus, not a DNA virus. Therefore, it does not need to integrate its genome into the host DNA before replication. Instead, it replicates its RNA genome directly in the host cell's cytoplasm.
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After assembly, the poliovirus causes the host cell to lyse, or break open, in order to release the newly formed viruses. Therefore, the statement that the viruses can be released without host cell lysis is incorrect.
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The poliovirus genome encodes both structural proteins, which make up the virus's capsid, and non-structural proteins, which are involved in the replication of the virus. Therefore, not all proteins encoded by the poliovirus genome form part of the capsid.
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The poliovirus polyprotein is not cleaved once into a structural and a non-structural protein. Instead, it is cleaved multiple times to produce several different proteins. Therefore, the statement that the polyprotein is cleaved once into a structural and a non-structural protein is incorrect.
Similar Questions
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