One reason that the Nurr1 nuclear receptor is an attractive target for Parkinson disease drugs is it's specific expression in dopaminergic neurons of the substantia nigra.Group of answer choicesTrueFalse

Which one of the following strategies is NOT used in the treatment of Parkinson’s disease?Group of answer choicesAgents that act as dopamine receptor agonists in the brain.Agents that diminish the actions of acetylcholine in the brain.Agents that inhibit dopa decarboxylase in the brain.Agents that decrease the breakdown of dopamine.

Degeneration of the dopamine-releasing neurons of the ________ is the ultimate cause of Parkinson's disease. substantia nigra internal capsule red nucleus reticular formation

Structure-Based Drug Design for Parkinson's Disease

Parkinson’s disease is a chronic progressive neurodegenerative disorder resulting in the loss of dopamine-producing cells in which brain structure? Group of answer choicesSubstantia nigraCingulate gyrusHippocampusHypothalamus

Loss of dopaminergic neurons in which brain structure leads to the motor symptoms of Parkinson’s disease?Group of answer choicesamygdalacerebellumhippocampussubstantia nigra