Structure-Based Drug Design for Parkinson's Disease

One reason that the Nurr1 nuclear receptor is an attractive target for Parkinson disease drugs is it's specific expression in dopaminergic neurons of the substantia nigra.Group of answer choicesTrueFalse

Which one of the following strategies is NOT used in the treatment of Parkinson’s disease?Group of answer choicesAgents that act as dopamine receptor agonists in the brain.Agents that diminish the actions of acetylcholine in the brain.Agents that inhibit dopa decarboxylase in the brain.Agents that decrease the breakdown of dopamine.

Design features of kinase inhibitors

This theory of drug refers to the certain portion of the drug molecule selectively combines with the molecular structure on the cell to produce physiological change.

Parkinson’s disease is a chronic progressive neurodegenerative disorder resulting in the loss of dopamine-producing cells in which brain structure? Group of answer choicesSubstantia nigraCingulate gyrusHippocampusHypothalamus