Homeostatic regulation of receptor levels often forms the basis of addiction. In Ralph's case the increased release of dopamine caused a progressive Multiple Choiceincrease in dopamine receptors in dopaminergic postsynaptic membranes.decrease in dopamine receptor numbers in dopaminergic postsynaptic membranes.increase in the levels of dopamine neurotransmitter release.
Question
Homeostatic regulation of receptor levels often forms the basis of addiction. In Ralph's case the increased release of dopamine caused a progressive Multiple Choiceincrease in dopamine receptors in dopaminergic postsynaptic membranes.decrease in dopamine receptor numbers in dopaminergic postsynaptic membranes.increase in the levels of dopamine neurotransmitter release.
Solution
The correct answer is "decrease in dopamine receptor numbers in dopaminergic postsynaptic membranes."
When there is an increased release of dopamine, the body tries to maintain balance or homeostasis by reducing the number of dopamine receptors in the postsynaptic membranes. This is because the body perceives that there is too much dopamine, so it tries to reduce its sensitivity to this neurotransmitter. This is also why people who use drugs that increase dopamine levels often need to use more and more of the drug to get the same effect - their bodies have reduced the number of dopamine receptors in response to the increased dopamine levels. This is a key mechanism in the development of addiction.
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