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Which of these is/are characteristic of MOST patients with Rheumatoid Arthritis?Question 35Select one:a.A pannus (hyperplastic synovium) leads to joint destruction.b.Type I or Type II hypersensitivity responsesc.Lack of circulating Rheumatoid Factord.Rheumatoid nodulese.Osteophyte formation

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Which of these is/are characteristic of MOST patients with Rheumatoid Arthritis?Question 35Select one:a.A pannus (hyperplastic synovium) leads to joint destruction.b.Type I or Type II hypersensitivity responsesc.Lack of circulating Rheumatoid Factord.Rheumatoid nodulese.Osteophyte formation

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Solution

The characteristics of most patients with Rheumatoid Arthritis include:

a. A pannus (hyperplastic synovium) leading to joint destruction: This is true. In Rheumatoid Arthritis (RA), the synovium, which is the thin layer of cells that lines our joints, becomes inflamed and thickened, creating a pannus. This pannus can invade and destroy the cartilage and bone within the joint, leading to loss of function and disability.

b. Type I or Type II hypersensitivity responses: This is not typically associated with RA. RA is actually considered a type III hypersensitivity reaction, where immune complexes are formed and deposited in tissues, causing inflammation and damage.

c. Lack of circulating Rheumatoid Factor: This is not true. Most patients with RA have an elevated level of Rheumatoid Factor (RF). RF is an autoantibody that is often found in the blood of people with RA, and its presence is one of the factors used to diagnose the disease.

d. Rheumatoid nodules: This is true. Rheumatoid nodules are firm lumps that grow under the skin near the affected joints. They are most commonly found on the elbows but can appear anywhere on the body. They are a common feature of RA and are often a sign of more severe disease.

e. Osteophyte formation: This is not typically associated with RA. Osteophytes, or bone spurs, are bony growths that form along the edges of bones, often in response to inflammation or damage. They are more commonly associated with oste

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