The main factor responsible for extrinsic pathway of apoptosis is:Select one:a. TNFb. Cytochrome cc. BCl2d. Caspases
Question
The main factor responsible for extrinsic pathway of apoptosis is:Select one:a. TNFb. Cytochrome cc. BCl2d. Caspases
Solution
The main factor responsible for the extrinsic pathway of apoptosis is:
a. TNF
The extrinsic pathway of apoptosis is triggered by external signals, such as the binding of death ligands (like TNF, Fas ligand) to their respective death receptors on the cell surface. This leads to the activation of caspases (like caspase 8 and 10), which are the main executioners of apoptosis. However, the initial trigger in this pathway is the binding of a death ligand to its receptor, so the correct answer is a. TNF.
Similar Questions
What is the role of caspases in apoptosis?
Apoptosis by the death receptor activation is most likely to occur by which of the following causes?Select one:a. Protein misfoldingb. Radiationc. DNA damaged. Viral infection
Which organelle is involved in the process of apoptosis?
extracellular messenger of apoptosis:
Apoptosis decreases the number of cells within various tissues of the body.Group startsTrue or FalseTrue, unselectedFalse
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