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Assume that a recessive allele (f) is associated with a severe language disorder. An unaffected male wants to determine the genotypes of his wife, his parents, and himself. His mother has the language disorder. Neither he nor his wife has the language disorder, but one of their five children does. What is the genotype for each individual? Answers may be used more than once or not at all. (Note: the gene associated with this language disorder is on an autosome.)Mother   Father   Wife   Himself

Question

Assume that a recessive allele (f) is associated with a severe language disorder. An unaffected male wants to determine the genotypes of his wife, his parents, and himself. His mother has the language disorder. Neither he nor his wife has the language disorder, but one of their five children does. What is the genotype for each individual? Answers may be used more than once or not at all. (Note: the gene associated with this language disorder is on an autosome.)Mother   Father   Wife   Himself

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Solution

The language disorder is associated with a recessive allele (f). This means that a person must have two copies of this allele (ff) to have the disorder.

  1. Mother: Since the mother has the language disorder, she must have two copies of the recessive allele. So, her genotype is ff.

  2. Father: The father does not have the disorder, but he has a child who does. This means he must carry the recessive allele but also has a dominant allele that prevents him from having the disorder. So, his genotype is Ff.

  3. Wife: The wife does not have the disorder, but she has a child who does. This means she must carry the recessive allele but also has a dominant allele that prevents her from having the disorder. So, her genotype is Ff.

  4. Himself: He does not have the disorder, but he has a child who does. This means he must carry the recessive allele but also has a dominant allele that prevents him from having the disorder. So, his genotype is Ff.

So, the genotypes are as follows:

Mother: ff Father: Ff Wife: Ff Himself: Ff

This problem has been solved

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