TDDSs have advantages and disadvantages as drug delivery systems. Indicate which of the following is an advantage and which is a disadvantage of TDDSs. You will use each answer more than once. - they avoid gastrointestinal difficulties and the first-pass effect - treatment can be terminated by removing the patch and are non-invasive - relatively potent drugs are used - skin reaction or dermatitis can occur at the site of application - they are used when oral administration is not advisable A. disadvantage B. advantage

Advantages of Matrix TDDS include all of the following, except : Question 11AnswerComplex formulation Excellent skin comfortabilitySimplified patch construction Efficient utilization of sizeLow dose dumping potential

Describe TWO advantages and TWO disadvantages of topical drug delivery for skin conditions.

The disadvantages of the oral route include all of the following, except:Question 17AnswerDestruction of some drugs by GI enzymes and secretionsGI irritationPossibility of irregular absorptionPossible food-drug interactionFast onset of action

Which of the following are advantages of suppositories and inserts as dosage forms? Select all that apply. A. large doses or irritating drugs can be given by suppository B. a suppository is such a dignified way to administer a drug C. a suppository avoids first pass effect and gastrointestinal degradation of the drug D. suppositories can be expelled by defecation E. commercially prepared suppositories are available in fewer dose levels F. administration of unpleasant tasting/smelling drugs is possible, especially for children

Advantages/Disadvantages of each system?What forms of treatment would you expect from eachsystem?