The longest primary transcript is generated by
Question
The longest primary transcript is generated by
Solution
The longest primary transcript is generated by the DMD (Dystrophin) gene. This gene is responsible for providing instructions for making a protein called dystrophin, which is located primarily in muscles used for movement and in heart (cardiac) muscle. Mutations in this gene can lead to Duchenne and Becker muscular dystrophies. The primary transcript (pre-mRNA) of the DMD gene is about 2.4 million bases long, making it the longest known human gene to be transcribed into RNA.
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Which of the following mRNA strands contains the longest open reading frame?A.5′-CCACGAUGCGUUGAGCGC-3′B.5′-CAAUGGUAAAGUCUUAGU-3′C.5′-GACGAUGUAACUUGCACU-3′D.5′-AGAAUGGUAUCCUGAGCC-3′
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