Which one of the following statements about the use of calcium channel antagonists for the treatment of hypertension is correct?Group of answer choicesThey cause relaxation of veins resulting in venous pooling and a decrease in preload.They cause arterial dilation and as a consequence decrease total peripheral resistance.They are contraindicated in patients with asthma.They inhibit T-type voltage-sensitive calcium channels.

The correct statement about the use of calcium channel antagonists for the treatment of hypertension is: They cause arterial dilation and as a consequence decrease total peripheral resistance.

Here's why:

1. Calcium channel antagonists work by blocking calcium channels in the heart and blood vessels. This reduces the amount of calcium that enters these tissues, which in turn causes the muscles in the heart and blood vessels to relax.

2. When the muscles in the blood vessels relax, the vessels dilate (widen). This reduces the resistance to blood flow, which is also known as total peripheral resistance.

3. By reducing total peripheral resistance, calcium channel antagonists lower blood pressure.

4. Therefore, the statement "They cause arterial dilation and as a consequence decrease total peripheral resistance" is correct.

The other statements are not correct:

• Calcium channel antagonists do not primarily cause relaxation of veins resulting in venous pooling and a decrease in preload. While they can have some effect on veins, their primary action is on arteries.

• They are not contraindicated in patients with asthma. In fact, some calcium channel antagonists can be used to treat certain symptoms of asthma.

• They do not inhibit T-type voltage-sensitive calcium channels. They primarily block L-type calcium channels, which are the main type of calcium channels in the heart and blood vessels.