Which one of the following statements regarding angiotensin AT1 receptor antagonists for the treatment of hypertension is correct?Group of answer choicesThey lower blood pressure via decreased angiotensin II levels.They decrease total peripheral resistance.They cause a dry cough.They decrease circulating angiotensin I levels.
Question
Which one of the following statements regarding angiotensin AT1 receptor antagonists for the treatment of hypertension is correct?Group of answer choicesThey lower blood pressure via decreased angiotensin II levels.They decrease total peripheral resistance.They cause a dry cough.They decrease circulating angiotensin I levels.
Solution
The correct statement regarding angiotensin AT1 receptor antagonists for the treatment of hypertension is: They decrease total peripheral resistance.
Here's why: Angiotensin AT1 receptor antagonists, also known as angiotensin receptor blockers (ARBs), work by blocking the action of angiotensin II, a chemical in your body that narrows your blood vessels. This blocking action causes the blood vessels to relax and widen, which decreases total peripheral resistance, thereby lowering blood pressure.
They do not lower blood pressure via decreased angiotensin II levels, but rather by blocking its effects. They also do not cause a dry cough - this is a side effect more commonly associated with ACE inhibitors, another class of blood pressure medications. Lastly, they do not decrease circulating angiotensin I levels. Angiotensin I is converted to angiotensin II in the body, and ARBs work by blocking the effects of angiotensin II, not by reducing angiotensin I levels.
Similar Questions
Select the correct statements. (Note that there may be more than one correct statement.)Group of answer choicesOne of the benefits of anticoagulant administration that these medications they thin blood (i.e., decrease blood viscosity) and therefore decrease blood pressure.One of the most common adverse effects of angiotensin II receptor antagonists is persistent, non-productive cough.ACE inhibitors decrease angiotensin II production and therefore decrease total peripheral resistance.β receptor antagonists decrease total peripheral resistance and evoke bronchodilation.
Which of the following statements is/are true regarding the long-term control of blood pressure?Question 8Select one or more:a.Aldosterone decreases water, sodium and chloride reabsorption at the kidney, increasing blood volume and blood pressure.b.Angiotensin II increases vasoconstriction of arterioles, increasing peripheral resistance and blood pressure.c.In response to falling blood pressure, levels of angiotensin II increase in the blood.d.Angiotensin II increases secretion of aldosterone from the adrenal cortex.e.The kidneys play an important role in the long-term control of blood pressure.
which of the following decreases blood pressure. a drug that:a) causes vasoconstrictionb) increases degradation of bradykininc) promotes aldosterone productiond) inhibits conversion of angiotensin I to II2 / 2
Which one of the following statements about the use of calcium channel antagonists for the treatment of hypertension is correct?Group of answer choicesThey cause relaxation of veins resulting in venous pooling and a decrease in preload.They cause arterial dilation and as a consequence decrease total peripheral resistance.They are contraindicated in patients with asthma.They inhibit T-type voltage-sensitive calcium channels.
Which one of the following statements about beta-adrenoceptor antagonists is INCORRECT?Group of answer choicesThey cause fatigue during exercise due to decreased cardiac output and skeletal muscle perfusion.They decrease blood pressure by decreasing heart rate.They decrease blood pressure by inhibiting renin secretion thereby lowering blood volume.They are safe in asthmatics.
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