Which of the following does not contribute to the glomerular hypercellularity in acute glomerulonephritis? Group of answer choicesrecruitment of inflammatory cellsproliferation of endothelial cellsproliferation of mesangial cellsproliferation of parietal epithelial cells
Question
Which of the following does not contribute to the glomerular hypercellularity in acute glomerulonephritis? Group of answer choicesrecruitment of inflammatory cellsproliferation of endothelial cellsproliferation of mesangial cellsproliferation of parietal epithelial cells
Solution
The option that does not contribute to the glomerular hypercellularity in acute glomerulonephritis is the proliferation of parietal epithelial cells.
Here's why:
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Recruitment of inflammatory cells: This contributes to glomerular hypercellularity as these cells infiltrate the glomerulus in response to inflammation, increasing the cell count.
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Proliferation of endothelial cells: Endothelial cells line the inside of the glomerulus. When these cells proliferate, they increase the cellularity of the glomerulus.
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Proliferation of mesangial cells: Mesangial cells are part of the glomerulus and their proliferation also contributes to an increase in glomerular cellularity.
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Proliferation of parietal epithelial cells: These cells line the Bowman's capsule, not the glomerulus. Therefore, their proliferation would not contribute to glomerular hypercellularity.
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