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Which one of the following cardiac biomarkers could detect a recent reinfarction?The correct answer is highlighted below Troponin I (TnI) Troponin T (TnT) Lactate dehydrogenase (LD) Creatine kinase MB (CK-MB)

Question

Which one of the following cardiac biomarkers could detect a recent reinfarction?The correct answer is highlighted below Troponin I (TnI) Troponin T (TnT) Lactate dehydrogenase (LD) Creatine kinase MB (CK-MB)

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Solution

The cardiac biomarker that could detect a recent reinfarction is Troponin I (TnI).

Here's why:

  1. Troponin I (TnI) and Troponin T (TnT) are both proteins found in heart muscle and are released into the blood when there is damage to the heart. They are highly specific for myocardial damage and are now the preferred markers for the diagnosis of myocardial infarction (heart attack).

  2. However, Troponin I (TnI) is more sensitive and specific than Troponin T (TnT) for detecting recent reinfarction. This is because TnI levels in the blood can remain elevated for 7-10 days after the initial heart damage, allowing for the detection of recent reinfarction.

  3. Lactate dehydrogenase (LD) and Creatine kinase MB (CK-MB) are also enzymes released into the blood during heart muscle damage. However, they are not as specific as troponins for heart damage and can also be elevated in conditions such as muscle injury or kidney disease.

  4. Therefore, among the options given, Troponin I (TnI) would be the best choice for detecting a recent reinfarction.

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