T cell independent activation of B cells:Select one alternative:is induced by antigens with repeated epitopes.results in production of predominantly IgG isotype.involves the separation of B cell receptors (BCRs) on the B cell surface.is more common than T cell dependent activation of B cells.
Question
T cell independent activation of B cells:Select one alternative:is induced by antigens with repeated epitopes.results in production of predominantly IgG isotype.involves the separation of B cell receptors (BCRs) on the B cell surface.is more common than T cell dependent activation of B cells.
Solution
The correct answer is: "is induced by antigens with repeated epitopes."
Here's why:
T cell independent activation of B cells is a process where B cells are activated without the help of T cells. This usually happens when the B cells encounter antigens with repeated epitopes. These antigens can cross-link the B cell receptors (BCRs) leading to the activation of the B cells.
The other options are incorrect because:
- T cell independent activation does not result in the production of predominantly IgG isotype. Instead, it mostly leads to the production of IgM antibodies.
- The process does not involve the separation of B cell receptors (BCRs) on the B cell surface. Rather, it involves the cross-linking of these receptors.
- T cell dependent activation of B cells is more common than T cell independent activation. This is because most protein antigens require T cell help to activate B cells.
Similar Questions
Compare and contrast T-dependent and T-independent activation of B cells
Similar to the need for a primary activation signal to fully activate T helper cells, a primary activation signal is needed to activate B cells by T-dependent antigens. Which of the following serves as the primary activation signal?ANSWERAn extracellular antigen binds to a B cell receptor.Cytokines are released upon proper T helper cell binding.The antigen enters the cell by endocytosis and is processed, and epitopes are displayed on the cell surface by MHC II.The MHC II–antigen complex on the B cell surface is bound by a T helper cell that can recognize the presented epitope.
What is the difference between a B cell and a T cell epitope?
When a B cell or T cell is stimulated by antigen, it divides, producing many identical copies of itself. This is an important part of the selection model.
Which of the following is a common feature between T and B cells?ANSWERBoth will undergo proliferation and differentiation to make plasma cells.Both mature in the bone marrow.Both require an antigen-presenting cell to become activated.Both produce memory cells after activation.
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