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The presence of which of the following antibodies would indicate a diagnosis of lupus nephritis (acute glomerulonephritis caused by SLE)?Group of answer choicesanti-deoxyribonucleoprotein (DNP) antibodiesanti-streptolysin-o (ASO) antibodies anti-glomerular basement membrane (GBM) antibodies

Question

The presence of which of the following antibodies would indicate a diagnosis of lupus nephritis (acute glomerulonephritis caused by SLE)?Group of answer choicesanti-deoxyribonucleoprotein (DNP) antibodiesanti-streptolysin-o (ASO) antibodies anti-glomerular basement membrane (GBM) antibodies

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Solution

The presence of anti-deoxyribonucleoprotein (DNP) antibodies would indicate a diagnosis of lupus nephritis (acute glomerulonephritis caused by SLE). These antibodies are often found in patients with systemic lupus erythematosus (SLE), a disease that can cause lupus nephritis when it affects the kidneys.

Here's a step-by-step explanation:

  1. Lupus nephritis is a kidney disorder that is a complication of SLE.

  2. SLE is an autoimmune disease, which means that the immune system attacks the body's own tissues and organs.

  3. In the case of lupus nephritis, the kidneys are being attacked by the immune system.

  4. This attack is often associated with certain antibodies that the immune system produces.

  5. One of these antibodies is the anti-deoxyribonucleoprotein (DNP) antibody.

  6. Therefore, the presence of anti-DNP antibodies in a patient's blood can indicate a diagnosis of lupus nephritis.

Please note that a diagnosis would involve other factors and tests as well, and would be made by a healthcare professional.

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