In the years before having her thyroid gland removed, a temporary decrease in Melissa's circulating thyroid hormone concentrations would have caused a compensatory response. Within the endocrine axis that includes thyroid hormone, which tissue(s) would respond to a temporary reduction in thyroid hormone concentration?A.Hypothalamus onlyB.Adrenal onlyC.Pituitary onlyD.Hypothalamus and pituitarySubmit
Question
In the years before having her thyroid gland removed, a temporary decrease in Melissa's circulating thyroid hormone concentrations would have caused a compensatory response. Within the endocrine axis that includes thyroid hormone, which tissue(s) would respond to a temporary reduction in thyroid hormone concentration?A.Hypothalamus onlyB.Adrenal onlyC.Pituitary onlyD.Hypothalamus and pituitarySubmit
Solution
The correct answer is D. Hypothalamus and pituitary.
Here's why:
The hypothalamus and pituitary gland are part of the hypothalamic-pituitary-thyroid axis, which regulates thyroid hormone production.
Step 1: When thyroid hormone levels are low, the hypothalamus responds by producing thyrotropin-releasing hormone (TRH).
Step 2: TRH then signals the pituitary gland to produce thyroid-stimulating hormone (TSH).
Step 3: TSH stimulates the thyroid gland to produce and release more thyroid hormone.
So, in response to a temporary reduction in thyroid hormone concentration, both the hypothalamus and pituitary gland would be involved in the compensatory response.
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