A 28-year-old, Caucasian male with a past medical history significant for non-nephrotic range proteinuria with micro-albuminuria presented to the hospital’s renal clinic. Laboratory results showed severe abnormalities in the non-haemolysed plasma specimen. These results were confirmed by repeat testing of the same sample.AnalyteResultPlasma reference intervalPotassium>15.0 mmol/L3.6 – 5.1Chloride121 mmol/L101 - 111Creatinine>2210 umol/L62 - 106The patient returned to the emergency department for evaluation, and laboratory results noted only low potassium (3.2 mmol/L). The initial laboratory results (above) are consistent with what type of specimen?Group of answer choicesplasmaserumsalivaurine
Question
A 28-year-old, Caucasian male with a past medical history significant for non-nephrotic range proteinuria with micro-albuminuria presented to the hospital’s renal clinic. Laboratory results showed severe abnormalities in the non-haemolysed plasma specimen. These results were confirmed by repeat testing of the same sample.AnalyteResultPlasma reference intervalPotassium>15.0 mmol/L3.6 – 5.1Chloride121 mmol/L101 - 111Creatinine>2210 umol/L62 - 106The patient returned to the emergency department for evaluation, and laboratory results noted only low potassium (3.2 mmol/L). The initial laboratory results (above) are consistent with what type of specimen?Group of answer choicesplasmaserumsalivaurine
Solution
The initial laboratory results are consistent with a urine specimen. The high levels of potassium and creatinine are typically seen in urine, not in plasma or serum. The reference intervals provided are for plasma, and the patient's results significantly exceed these, which is another clue that the specimen is likely urine. Additionally, the presence of non-nephrotic range proteinuria with micro-albuminuria in the patient's medical history suggests a kidney issue, which would be investigated through urine testing.
Similar Questions
A 36-year-old man presents with the following blood biochemistry results:Analyte (SERUM)ResultReference intervalSodium146135 – 145 mmol/LPotassium6.83.5 – 5.5 mmol/LChloride10895 – 110 mmol/LBicarbonate2222 – 32 mmol/LUrea36.63.0 – 8.0 mmol/LCreatinine37740 – 90 μmol/LeGFR50> 90 ml/min/1.73m2Considering the abnormal results, what is the likely diagnosis for this patient?Group of answer choicesHe has acute kidney diseaseHe is on thiazide diureticsHe has metabolic acidosisHe has chronic diarrhea
Sodium 136 mEq/LPotassium 2.6 mEq/LChloride 93 mEq/LBicarbonate 34 mEq/LBlood urea nitrogen 9 mg/dLCreatinine 0.8 mg/dLGlucose 150 mg/dL (non-fasting)Magnesium 0.6 mEq/L Arterial blood gas pH 7.50 PaO2 95 mmHg PaCO2 48 mmHg Urine studies show high levels of potassium and chloride, and low levels of calcium. Which of the following conditions would produce similar findings to this patient's disease?
IV. Classification of CKD with changes of urine analysis
28-year-old man presents to the ER with a large amount of blood and protein in his urine. He has had a sensorineural hearing loss since his teen years and has misshaped lenses (anterior lenticonus). The physician is suspicious of a genetic disorder that may lead to eventual kidney failure. If this is the case, the patient most likely has a mutation in which one of the following proteins?
Haematuria (blood in the urine) indicates:Group of answer choicesdamage to the glomerular filtration barriernormal kidney function (small amounts of blood in the urine is normal)increased glomerular basement membrane permeabilityurinary tract infection
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