Which of the following statements about the process of wound healing are true?Question 8Select one:a.The remodelling phase involves fibroblast activity and production of collagen.b.Inflammatory phase begins 2-3 days after the injury.c.The white cells stick to the damaged endothelium and release cytokines.d.Proliferative phase lasts from 3 days to 3 weeks following the injury.e.Fibroblasts do not require vitamin C to produce collagen.
Question
Which of the following statements about the process of wound healing are true?Question 8Select one:a.The remodelling phase involves fibroblast activity and production of collagen.b.Inflammatory phase begins 2-3 days after the injury.c.The white cells stick to the damaged endothelium and release cytokines.d.Proliferative phase lasts from 3 days to 3 weeks following the injury.e.Fibroblasts do not require vitamin C to produce collagen.
Solution
The correct answer is:
a. The remodelling phase involves fibroblast activity and production of collagen. This is true. During the remodelling phase, fibroblasts produce collagen, which helps to strengthen the wound.
c. The white cells stick to the damaged endothelium and release cytokines. This is also true. White blood cells, or leukocytes, adhere to the damaged endothelium in a process called margination. They then release cytokines, which are signaling molecules that promote inflammation and attract more white blood cells to the site of injury.
d. Proliferative phase lasts from 3 days to 3 weeks following the injury. This is true as well. The proliferative phase of wound healing involves the growth of new tissue to replace what was lost in the injury. This phase typically begins a few days after the injury and can last for several weeks.
The other statements are false:
b. Inflammatory phase begins 2-3 days after the injury. This is false. The inflammatory phase of wound healing actually begins immediately after the injury. It's characterized by hemostasis (the cessation of bleeding) and inflammation.
e. Fibroblasts do not require vitamin C to produce collagen. This is false. Vitamin C is a necessary cofactor for the enzymes that fibroblasts use to produce collagen. Without it, collagen synthesis is impaired.
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