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A 4-year-old girl has the following blood indices:Hb 50 g/LMCV 62 fLWBC and platelets are normalreticulocytes are 500 x 109/L (upper normal limit is 100 x 109/L)She most likely has:Question 6Select one:a.Pernicious anaemiab.Hereditary spherocytosis syndromec.autoimmune haemolytic anaemiad.iron deficiency anaemiae.Thalassemia

Question

A 4-year-old girl has the following blood indices:Hb 50 g/LMCV 62 fLWBC and platelets are normalreticulocytes are 500 x 109/L (upper normal limit is 100 x 109/L)She most likely has:Question 6Select one:a.Pernicious anaemiab.Hereditary spherocytosis syndromec.autoimmune haemolytic anaemiad.iron deficiency anaemiae.Thalassemia

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Solution

The girl's symptoms suggest that she most likely has d. iron deficiency anaemia.

Here's why:

  1. The girl's Hemoglobin (Hb) level is 50 g/L, which is significantly lower than the normal range for a 4-year-old girl (110-120 g/L). This indicates that she has anaemia.

  2. Her Mean Corpuscular Volume (MCV) is 62 fL, which is lower than the normal range (70-86 fL). A low MCV is a sign of microcytic anaemia, which is often caused by iron deficiency.

  3. Her White Blood Cell (WBC) and platelet counts are normal, which rules out conditions that would cause an increase or decrease in these counts, such as pernicious anaemia or autoimmune haemolytic anaemia.

  4. Her reticulocyte count is 500 x 109/L, which is significantly higher than the upper normal limit (100 x 109/L). A high reticulocyte count indicates that her body is producing more of these immature red blood cells to make up for the lack of mature ones, which is a common response to anaemia.

  5. Hereditary spherocytosis syndrome and thalassemia are both genetic disorders that cause anaemia, but they would likely present with other symptoms and abnormal blood indices. For example, hereditary spherocytosis often causes jaundice and an enlarged spleen, and thalassemia usually causes a high MCV, not a low one.

Therefore, based on the girl's blood indices and the absence of other symptoms, she most likely has iron deficiency anaemia.

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