A 35‐year‐old man is diagnosed with acute myeloid leukaemia with normal karyotype. FLT3 internal tandem duplication is present, while nucleophosmin is wild type and a 22‐gene molecular panel shows no further mutations. Which ONE of the following is the most appropriate initial therapy for this patient? (P) A Combination chemotherapy and midostaurin B Immediate allogeneic stem cell transplantation with myeloablative conditioning C Gemtuzumab ozogamicin, hydroxycarbamide and decitabine D Combination chemotherapy and dasatinib

A 74‐year‐old man is diagnosed with acute myeloid leukaemia with trisomy 8 karyotype and asks about his approximate long‐term cure rate with the best available therapy. Which ONE of the following is the most accurate answer? A His condition is incurable B 60% C 30% D 10%

A 54‐year‐old man was diagnosed earlier today with acute myeloid leukaemia. Therapy has not yet been initiated. Which ONE of the following full blood count results is most likely in this patient? A Hb 140 g/L; WBC 270 × 109/L; platelets 100 × 109/L B Hb 90 g/L; WBC 2 × 109/L; platelets 140 × 109/L C Hb 90 g/L; WBC 27 × 109/L; platelets 10 × 109/L D Hb 140 g/L; WBC 270 × 109/L; platelets 940 × 109/L

A 27‐year‐old woman presents to her general practitioner with fatigue and easy bruising. A full blood count shows pancytopenia, and she is admitted to the hospital. The partial thromboplastin and prothrombin time (international normalized ratio) are both abnormal, and fragmented red cells are noted on blood film. Which ONE of the following is the most likely diagnosis in this case? A Acute lymphoblastic leukaemia B Acute promyelocytic leukaemia C Acute monoblastic leukaemia D Acute myeloid leukaemia without differentiation

When three copies of a specific chromosome are present in a cell, this is called Blank______Multiple choice question.karyosomytrisomytrichromosomymonosomy

Select the two types of treatments that have successfully cured children born with severe combined immunodeficiency (SCID).Multiple select question.Highly active antiretroviral therapy (HAART)Long-term antibiotic therapyGene therapyAnti-IgE antibodiesBone marrow transplantation