Which of the following statements about cancer cells is correct?1. Passenger mutations can occur without the onset of a tumor.2. Cancer cells are derived from a clone.3. Accumulation of driver mutations can lead to cancer.4. Intratumoral heterogeneity provides a good rationale for advancing precision medicine.A. 1, 2 and 3B. 1 and 3C. 2 and 4D. 4 onlyE. All of 1, 2, 3 and 4 are correc

Which of the following statements about cancer cells is correct?1. Passenger mutations can occur without the onset of a tumor.2. Cancer cells are derived from a clone.3. Accumulation of driver mutations can lead to cancer.4. Intratumoral heterogeneity provides a good rationale for advancing precision medicine.A. 1, 2 and 3B. 1 and 3C. 2 and 4D. 4 onlyE. All of 1, 2, 3 and 4 are correct.23. Which of the following statements about genetics of Alzheimer’s Disease (AD) is correct?A. Mutations in presenilin 1 or 2 can lead to AD.B. Production of ApoE3 can lead to AD.C. Trisomy 21 decreases the probability of early onset.D. Decrease in β-secretase can lead to AD.24. Theoretically, which of the following could be used as a biomarker (something you test for to see if thedisease could be present) for Alzheimer’s Disease?1. Hyperphosphorylated Tau.2. 42aa β-amyloid peptide.3. Acetylcholine production.4. Glutamate production.A. 1, 2 and 3B. 1 and 3C. 2 and 4D. 4 onlyE. All of 1, 2, 3 and 4 are correct.

When dealing with the concept of mutations in the first unit (i.e. heredity), what statement is incorrect about mutations? Question 21 options: Mutations do not impact the normal operations of the cell Carcinogens cause mutations to form Occur in sex cells (gametes) Mutations can often arise spontaneously.

Which of the following statements regarding a malignant tumour is INCORRECT?Group of answer choicesIt is generally fast growing.It does not have a capsule.It has highly differentiated cells.It invades surrounding structures or metastasise.

Which of the following statements is true about mutations?i. They can produce new alleles of existing genes.ii. They can be inherited if they are in somatic cells.iii. They may affect a single codon or a part of a chromosomeiv. They are always linked to diseasei, ii and iiii and iiiii and iiii, ii, iii and iv

Which of the following statements is INCORRECT?Group of answer choicesDamaged DNA is usually repaired by cells.Mutations are more likely to occur in rapidly dividing cells.Cells with damaged DNA often undergo apoptosis.Promotors cause mutations in DNA.