Haemophilia is an X-linked, recessive genetic disorder. A male haemophiliac will transmit the haemophilia allele to:Question 6Select one:a.all of his daughters.b.all of his sons.c.half of his daughters.d.half of his sons.
Question
Haemophilia is an X-linked, recessive genetic disorder. A male haemophiliac will transmit the haemophilia allele to:Question 6Select one:a.all of his daughters.b.all of his sons.c.half of his daughters.d.half of his sons.
Solution
The correct answer is a. all of his daughters.
Here's why:
Haemophilia is an X-linked recessive disorder. This means the gene for haemophilia is located on the X chromosome. Males have one X and one Y chromosome (XY), and females have two X chromosomes (XX).
When a male haemophiliac (who would be XhY, 'h' denoting the haemophilia allele) has children, he gives either his X or his Y chromosome to his offspring.
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If the child is a son, the son receives the Y chromosome from his father (because sons are XY, and they must receive a Y from their father to be male). So, the son cannot receive the X chromosome carrying the haemophilia allele from his father. Therefore, a male haemophiliac cannot transmit the disorder to his sons.
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If the child is a daughter, the daughter receives the X chromosome from her father (because daughters are XX, and they must receive one X from their mother and one X from their father). So, all daughters of a male haemophiliac will receive the X chromosome carrying the haemophilia allele. Therefore, a male haemophiliac will transmit the haemophilia allele to all of his daughters.
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