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Long-term potentiation:Group of answer choicesalways exhibits associativityalways requires protein synthesis for inductionalways results in increased excitatory post-synaptic potentialsalways involves NMDA receptorsis only found in hippocampus

Question

Long-term potentiation:Group of answer choicesalways exhibits associativityalways requires protein synthesis for inductionalways results in increased excitatory post-synaptic potentialsalways involves NMDA receptorsis only found in hippocampus

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Solution

Long-term potentiation (LTP) is a process that plays a key role in the strengthening of synapses, which is crucial for learning and memory. Here are the answers to your options:

  1. Always exhibits associativity: Yes, LTP does exhibit associativity. This means that if two synapses on a neuron are stimulated at the same time, they are both strengthened. This is a key property of LTP and is part of why it is thought to be so important for learning and memory.

  2. Always requires protein synthesis for induction: No, LTP does not always require protein synthesis for induction. Early-phase LTP can occur without new protein synthesis, but late-phase LTP, which results in more lasting changes, does require protein synthesis.

  3. Always results in increased excitatory post-synaptic potentials: Yes, LTP generally results in increased excitatory post-synaptic potentials (EPSPs). This is because LTP strengthens the synapse, which makes the post-synaptic neuron more likely to fire in response to a given amount of pre-synaptic stimulation.

  4. Always involves NMDA receptors: Yes, LTP often involves NMDA receptors. These receptors are crucial for the induction of LTP because they allow calcium ions to enter the neuron, which triggers the intracellular processes that lead to LTP.

  5. Is only found in the hippocampus: No, LTP is not only found in the hippocampus. While the hippocampus is a key site of LTP and is crucial for certain types of memory, LTP can also occur in other parts of the brain.

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