Long-term depression in mammalian brain does not:Group of answer choicesbecome induced following changes in intracellular Ca++ in some neuronsinvolve a stimulus-dependent increase in excitatory postsynaptic potential (EPSP)cause reversal of long-term potentiation in some neuronscontribute to motor learning in the cerebellumpersist for at least 60 minutes following induction

Question 201 ptsWhich of the following mechanisms is involved in long-term depression (LTD) in the cerebellum?Group of answer choicesactivation of metabotropic glutamate receptorsa reduction in Ca2+ concentration in Purkinje cell dendritesinactivation of Protein Kinase Csensitisation of NMDA receptorssensitisation of AMPA receptors Previous

Which of the following is NOT involved in the induction of long-term depression in Purkinje cells in the cerebellum?Group of answer choicesActivation of NMDA receptorsActivation of parallel fibresActivation of metabotropic glutamate receptorsActivation of AMPA receptorsActivation of climbing fibres

Which of the following is a feature of long term potentiation?Group of answer choiceslong-term potentiation synaptic strengthening lasts about 24 hourshigh levels of glutamate release are necessary over long periods of timeit can only occur in the hippocampus CA3 and CA1 fields pyramidal cellsit occurs in the amygdala and prefrontal cortexit develops when presynaptic and postsynaptic neurons fire simultaneous

Long-term potentiation:Group of answer choicesalways exhibits associativityalways requires protein synthesis for inductionalways results in increased excitatory post-synaptic potentialsalways involves NMDA receptorsis only found in hippocampus

Which of the following is a major function of the cerebellum?Group of answer choicesAlter local circuits of the brainstem and spinal cord via direct projections to the lower motor neuronsAnalyze errors between intended motor output and actual motor outputModulate the output of the basal gangliaRelay information from the primary somatosensory cortex to the primary motor cortexModulate and relay executive decision-making information from the prefrontal cortex to the rest of the cerebral cortex