Which of these signs, symptoms and pathological hallmarks is attributed to the correct disease?Question 1Answera.Excess chloride ion excretion from cells and thin, watery mucus in lungs - CYSTIC FIBROSIS.b.Increased respiratory rate and reduced CO2 in blood - CHRONIC BRONCHITIS.c.Metaplasia of epithelial cells in the bronchi - PNEUMONIA.d.Increased protease and reduced anti-protease activity in alveoli - EMPHYSEMA.e.Reduced inflammation in lungs, no alveolar wall damage and high blood O2 saturation - COVID-19.
Question
Which of these signs, symptoms and pathological hallmarks is attributed to the correct disease?Question 1Answera.Excess chloride ion excretion from cells and thin, watery mucus in lungs - CYSTIC FIBROSIS.b.Increased respiratory rate and reduced CO2 in blood - CHRONIC BRONCHITIS.c.Metaplasia of epithelial cells in the bronchi - PNEUMONIA.d.Increased protease and reduced anti-protease activity in alveoli - EMPHYSEMA.e.Reduced inflammation in lungs, no alveolar wall damage and high blood O2 saturation - COVID-19.
Solution
The correct attributions of signs, symptoms and pathological hallmarks to diseases are as follows:
a. Excess chloride ion excretion from cells and thin, watery mucus in lungs - CYSTIC FIBROSIS. This is correct. Cystic fibrosis is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. It is characterized by the production of abnormally viscous mucus, due to mutation in a gene that codes for a protein involved in the transport of chloride ions.
b. Increased respiratory rate and reduced CO2 in blood - CHRONIC BRONCHITIS. This is incorrect. Chronic bronchitis is characterized by increased CO2 in the blood (not reduced), due to impaired ability to expel air from the lungs.
c. Metaplasia of epithelial cells in the bronchi - PNEUMONIA. This is incorrect. Metaplasia of epithelial cells in the bronchi is more commonly associated with chronic bronchitis or lung cancer, not pneumonia. Pneumonia is an infection that inflames the air sacs in one or both lungs, which may fill with fluid.
d. Increased protease and reduced anti-protease activity in alveoli - EMPHYSEMA. This is correct. Emphysema is a type of chronic obstructive pulmonary disease (COPD) characterized by damage to the air sacs (alveoli) in the lungs. This is often due to an imbalance between protease (an enzyme that breaks down proteins) and anti-protease (a protein that inhibits the proteases) activity in the lungs.
e. Reduced inflammation in lungs, no alveolar wall damage and high blood O2 saturation - COVID-19. This is incorrect. COVID-19 often causes significant inflammation in the lungs, potential alveolar wall damage, and can lead to low blood O2 saturation, especially in severe cases.
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