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Receptors of opioids are present in :-A CNS B Spleen C GIT D Both (1) and (3)

Question

Receptors of opioids are present in :-A CNS B Spleen C GIT D Both (1) and (3)

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Solution

The receptors of opioids are present in both the Central Nervous System (CNS) and the Gastrointestinal Tract (GIT). Therefore, the correct answer is D. Both (1) and (3).

Here's a step-by-step explanation:

  1. Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands.

  2. These receptors are distributed widely in the body. They are found in the central and peripheral nervous system and in the gastrointestinal tract.

  3. In the CNS, they are found in areas involved in pain perception and reward, such as the periaqueductal gray, the ventral tegmental area, the nucleus accumbens, and the spinal cord.

  4. In the GIT, they are found in the myenteric and submucosal plexus. They play a role in motility, secretion, and absorption.

  5. Therefore, the receptors of opioids are present in both the CNS and the GIT.

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