Which of the following is the cause of sickle cell anemia?*1 pointTryptophan is replaced by leucineLeucine is replaced by valineGlutamic acid is replaced by valineLysine is replaced by glutamic acid

In Sickle-Cell disease is caused by a mutation in a gene that codes for one of the protein's subunits. Which one of the following statements about this disease is correct?Group of answer choicesThe mutation is due to a silent mutation within the alpha subunit that changes an electrically charged amino acid to another electrically charged amino acid.acid.The mutation is due to a missense mutation within the beta subunit that changes an electrically charged amino acid to a nonpolar amino acid.The mutation is due to a missense mutation within the alpha subunit that changes an electrically charged amino acid to a nonpolar amino acid.The mutation is due to a silent mutation within the beta subunit that changes an electrically charged amino acid to another electrically charged amino.

Briefly describe each of the commonly occurring mutations of haemoglobin (thalassemia and sickle cell) and how these affect haemoglobin production and function.

Sickle cell anemia is caused by a allele because this mutation has more than one effect on the phenotype.

Which of the following describes sickle-cell disease? Multiple select question.Red blood cells take on a translucent appearance.It is a hereditary condition.The heme part of hemoglobin is abnormal.Red blood cells are misshapen.It can be caused by iron deficiency.

Bonus question: Can anyone explain how the shape of red blood cells differs in people with sickle cell anemia? What complications does this cause?